The AO Research Institute (ARI) Davos is looking for a PostDoc to investigate the interaction between immune cells and biomaterials, with the ultimate goal of establishing design principles for biomaterials controlling inflammation for improved bone healing. Previous experience in cell culture, biochemistry assays, proteomics; confocal microscopy; handling of immune cells will be valued; 3D (bio)printing, and chemical modification of biopolymers, is a plus. Strong motivation is essential.

ARI's Biomedical Materials Focus Area is committed to designing advanced biomaterials and the development of manufacturing technologies for improved musculoskeletal disorders therapies. We offer training at the forefront of biomaterials research in the context of a world-renewed musculoskeletal research institute; a challenging and rewarding research and educational program within a unique global organization based in Davos that offers urban flair in a pristine natural environment; a wide international network with the best scientists in the field, support searching for accommodation; networking opportunities to prepare the candidate for the next step in her/his career.

Topic: Interaction between immune cells and biomaterials

The successful candidate will be studying how neutrophils and macrophages interact with biomaterials, determining the interplay between chemical composition, bulk and local mechanical properties and surface topography on inflammation. This knowledge will be then harnessed with advanced biofabrication techniques to create biomaterials constructs controlling inflammation with the ultimate goal of improving regeneration of musculoskeletal tissues after trauma and disease. This project is closely connected with numerous other projects within ARI.

• Strong motivation and interest in the research topic
• PhD degree in Biology, Immunology, Biomedical Engineering, Health Sciences and Technology, or similar disciplines
• Excellent laboratory skills in cell culture, biochemistry assays, proteomics; confocal microscopy. Previous experience with laboratory handling of immune cells, 3D (bio)printing, chemical modification of biopolymers, is a plus
• Accurate and reliable with a high work ethic standards
• Familiarity with a cross-cultural/interdisciplinary environment is an advantage.
• Fluency in English
• Eligibility to apply and obtain a Visa for temporary residence is Switzerland is essential
• The preferred starting date is the last quarter ofDuration: 2 years